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by Rachidi, M. et al.
Laboratory of Genetic Dysregulation Models: Trisomy 21 and Hyperhomocysteinemia, EA 3508, University Paris 7-Denis Diderot, Paris, France

DOPEY2 overexpression in the brain regions, that are altered in Down syndrome patients and involved in learning and memory processes, is in agreement to the hypothesis that this gene plays a potential role in functional brain alterations and in the pathogenesis of mental retardation in Down syndrome.
Int. J. Dev. Neurosci. 2009; 4:393-8

[See paper]

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